منابع مشابه
Sustained stress response after oxidative stress in trabecular meshwork cells
PURPOSE To investigate the mechanisms by which chronic oxidative stress may lead to a sustained stress response similar to that previously observed in the trabecular meshwork (TM) of glaucoma donors. METHODS Porcine TM cells were treated with 200 microM H2O2 twice a day for four days and were allowed to recover for three additional days. After the treatment, TM cells were analyzed for generat...
متن کاملLocalization of the Stress Proteins aB-Crystallin and Trabecular Meshwork Inducible Glucocorticoid Response Protein in Normal and Glaucomatous Trabecular Meshwork
RESULTS. In normal eyes, labeling for aB-crystallin occurred in the subendothelial region of Schlemm's canal and outer corneoscleral regions, whereas TIGR labeling was found in the inner uveal meshwork region and the anterior portion of the meshwork. In contrast, in many glaucomatous eyes, labeling for aB-crystallin and TIGR occurred in more regions of the meshwork and appeared more intense tha...
متن کاملLocalization of the stress proteins alpha B-crystallin and trabecular meshwork inducible glucocorticoid response protein in normal and glaucomatous trabecular meshwork.
PURPOSE To examine the differential staining of two potential stress-response markers, alpha B-crystallin and the trabecular meshwork inducible glucocorticoid response protein (TIGR), in meshwork from normal and glaucomatous human eyes. METHODS Trabecular meshwork from 35 eyes from 23 donors with either primary open-angle glaucoma, pseudoexfoliative glaucoma, or low-tension glaucoma, and from...
متن کاملEffects of Mechanical Stress on Human Trabecular Meshwork Cells
BACKGROUND: High intraocular pressure (IOP) is a major risk factor for glaucoma.
متن کاملCalf Trabecular Meshwork
Superoxide dismutase and catalase activities have been measured in cell-free extracts of calf trabecular meshwork, and for comparison, in calf iris, retina, lens, liver, and erythrocytes. Gel electrophoresis has been used to identify isozymes of each enzyme. The superoxide dismutase and catalase activities per milligram wet weight of calf trabecular meshwork, 0.184 and 0.884 U/mg wet wt, respec...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Glaucoma
سال: 2008
ISSN: 1057-0829
DOI: 10.1097/ijg.0b013e31815f52a8